Skip to main content
. Author manuscript; available in PMC: 2009 Jun 25.
Published in final edited form as: Circulation. 2007 Jun 11;115(25):3197–3204. doi: 10.1161/CIRCULATIONAHA.106.657981

Figure 4. E2 upregulates the myocardial Trx system.

Figure 4

A, Trx1, TrxRD1, Trx2, and TrxRD2 mRNA expression levels in FVB and Gq mice at 8 weeks after placebo or E2 pellet implantation, analyzed by Northern blot. Expression levels of each mRNA were relative to those of GAPDH mRNA (n=9 in each group). Results are presented as mean±SD. *P<0.05 compared with placebo-treated FVB mice. †P<0.05 compared with placebo-treated Gq mice. B, TrxRD activity in mitochondrial and cytosolic fraction samples of hearts of FVB and Gq mice at 8 weeks after placebo or E2 pellet implantation (n=10 in each group). Results are presented as mean±SD. *P<0.05 compared with placebo-treated FVB mice. †P<0.05 compared with placebo-treated Gq mice.