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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Am J Trop Med Hyg. 2008 Nov;79(5):760–767.

FIGURE 7.

FIGURE 7

Intestine lumen diameter measured at the region of the kidney in transverse magnetic resonance imaging (MRI) images. Lumen diameter was compared at the acute (A, 30 dpi) and chronic (C, 60 dpi) for all groups except NOS1 (no infected NOS1 null mice survived to the 60 days time point). Wild-type uninfected (WTU) is the average of 29 measurements (4 mice); WT I A (wild type infected, 30 dpi) is the average of 31 measurements (5 mice); WT I C (wild type infected, 60 dpi) is the average of 10 measurements (2 mice); NOS1 null U (NOS1 null uninfected) = 55 measurements (9 mice); NOS1 null I A (NOS1 null infected, 30 dpi) = 23 measurements (5 mice); NOS2 null U (NOS2 null uninfected) = 29 measurements (5 mice); NOS2 null I A (NOS2 null infected, 30 dpi) = 42 measurements (7 mice); NOS2 null I C (NOS2 null infected, 60 dpi) = 12 measurements (2 mice); NOS3 null U (NOS3 null uninfected) = 28 measurements (4 mice); NOS3 null I A (NOS3 null infected) = 18 measurements (3 mice); NOS3 null I C (NOS3 null infected) = 7 measurements (1 mouse). *Lumen diameter was significantly increased in all infected mouse groups compared with their respective uninfected groups (t test, P < 0.001 for WT, NOS2 null, and NOS3 null, and P = 0.018 for NOS2 null). The extent of increase in lumen diameter during acute versus chronic infection was not significantly different for the WT, NOS2 null, and NOS3 null mice.