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. 2009 Jun 1;119(7):1974–1985. doi: 10.1172/JCI33816

Figure 4. Ad-RAD50 enhances cisplatin-induced suppression of SCC cell growth.

Figure 4

(A) Combining Ad-RAD50 and cisplatin in JHU012 SCC cells produced a reduction in cell growth within 48 hours and a persistent suppression of cell proliferation relative to all other groups (P < 0.01). DL312 indicates DL312 control virus. (B) The addition of Ad-RAD50 to cisplatin treatment in JHU029 cells produced the greatest reduction in cell growth versus all other groups (P < 0.01). Cells were cloned from parental cell lines. Mean optical density ± SEM is shown.