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. 2009 Jun 1;119(7):1974–1985. doi: 10.1172/JCI33816

Figure 8. Quantification of apoptosis in human head and neck cancer tumors.

Figure 8

(A) TUNEL staining was performed on tumor SCC samples after tumor harvest. A selection of 1 high-powered field (original magnification, ×40) from each treatment group is shown. (B) Mean percentage apoptosis per high-powered field ± SEM is shown. The combination of Ad-RAD50 and cisplatin enhanced induction of apoptosis relative to all other groups (P < 0.001). This is consistent with the tumor volume reduction seen in the combination therapy groups.