Figure 4. In vivo selection in SIV-transduced animal RQ4099 after 1 cycle of BG/TMZ.

Rhesus competitive repopulation experiments were set up using equal numbers of mobilized PB CD34⁺ cells transduced with SIV vectors expressing MGMT*-YFP or MGMT*-HOXB4-GFP. (A) Percent GFP⁺ and YFP⁺ granulocytes and monocytes from PB. (B) Percent GFP⁺ and YFP⁺ B cells and T cells from PB. Arrows denote cycles of drug administration.