(A) Immunodetection of the nuclear adduct 8-oxodG in cauda epididymidis-retrieved spermatozoa preparations from 6-month-old WT, KO, or hydrogen peroxide–treated WT male mice. Images are representative of several distinct detections. (B) Histograms showing the percentage of 8-oxodG–positive spermatozoa in cauda epididymidis-retrieved spermatozoa preparations, from 6-month-old WT, KO, and positive control (WT spermatozoa treated with hydrogen peroxide) male mice. Data are mean ± SEM. n = 3. **P < 0.05.