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. 2009 Jul 8;4(7):e6184. doi: 10.1371/journal.pone.0006184

Table 3. T cells subsets (CD4+/CD8+) and T-cell activation markers (HLA-DR+, CD69+, CD25+, CD45RA+, CD45RA, CD62L) in peripheral blood mononuclear cells for surveys 1 and 2.

Blood T cells
Surface antigen controls patients
n = 27 n = 33
CD4/CD8 (1) 1.1±0.8 1.3±0.6
n = 13 n = 17
CD4+ (2) HLA-DR+ 23.0±4.2 26.9±5.0
CD8+ HLA-DR+ 45.5±14.8 45.9±12.6
CD8+ CD69+ 1.2±0.5 1.0±0.4
n = 14 n = 16
CD4+ (3) CD25+ 3.0±1.0* 0.3±0.2*
CD8+ CD25+ 0.4±0.5 0.2±0.1
n = 13 n = 17
CD4+ (2) CD45RA+ 12.9±6.9 10.3±5.6
CD4+CD62L+ CD45RA+ 19.9±9.0* 30.1±12.8*
CD8+ CD45RA+ 48.3±21.1 41.9±15.6
CD8+CD62L+ CD45RA+ 12.2±11.6* 23.3±12.3*
CD4+CD62L+ CD45RA 24.7±12.2* 42.8±15.7*
CD8+CD62L+ CD45RA 15.2±12.3 21.2±11.2
CD8+ CD62L CD45RA+ 87.8±11.6* 76.7±12.4*
CD8+ CD62L CD45RA 84.8±12.4 78.7±11.1

(1) n = 33 patients and 27 controls from both surveys.

(2) n = 16 patients and 14 controls from survey 2.

(3) n = 17 patients and 13 controls from survey 1. Data are expressed in percentages of total lymphocyte events acquired with the FACSCalibur (104 on average)±standard deviation.

*

Significant difference between controls and patients (P<0.05).