Table 1. Radiotherapy (RT,) patterns of failure, and outcome.

RT after surgical resection is designated “adjuvant” and RT to an uninvolved site is designated “elective”. In all other cases RT was delivered for gross disease.

	Target and intent in 1st RT course	Site of failure after 1st RT course	Target and intent in 2nd RT course	Site of failure after 2nd RT course	Survival after the diagnosis of CPNI (months)	current status
1	nerves*	treated nerves	nerves	N/A†	66m	alive
2	skin-adjuvant*	nerves	nerves	contiguous nerves	17m	alive
3	skin and nerves	skin and contiguous nerves	nerves-palliative		60m	dead
4	skin-adjuvant	nerves	nerves	contiguous nerves	80m	alive
5	skin-adjuvant*	skin and nerves	skin and nerves-adjuvant	N/A†	4m	alive
6	skin-adjuvant*	skin and nerves	skin and nerves-adjuvant, nodes-elective	skin and contiguous nerves	22m	dead
7	skin and nerves – adjuvant, nodes-elective	contiguous nerves	nerves	treated and contiguous nerves	13m	alive
8	skin and nerves-adjuvant, nodes-elective	N/A†			39m	alive
9	Skin and nerves. nodes-elective	N/A†			10m	alive
10	skin-adjuvant	nerves contiguous	nerves-palliative	radiotherapy discontinued after 12.5 Gy	2m	dead
11A††	Nerves. Nodes-elective.	nerves	nerves	N/A	28m	alive
11B	Skin. Nerve and nodes-elective.	contiguous nerve

^*RT was delivered in another facility.

^†N/A=not applicable (no evidence for disease recurrence)

^††Patient 11 was synchronously diagnosed with bilateral tumors with clinical perineural invasion (CPNI) which were considered as two separate cases.