Table 3.
Potential symbiosis-related genes identified from the Aiptasia transcriptome
| Name | UniSeq example | SwissProt Accession | E-value blastx | Notes |
| Oxidative stress-/antioxidant activity-related | ||||
| 1-Cys peroxiredoxin | CCAS1731.g1 | O17433 | 3.00E-45 | Thiol specific antioxidant |
| Catalase | Contig514 | P04040 | 0 | Homolog to catalase |
| Peroxidase/catalase | Contig1300 | O59651 | 1.00E-26 | Catalase and peroxidase activity |
| Dual oxidase | Contig42 | Q9VQH2 | 8.00E-41 | Anti-microbial oxidative burst |
| L-ascorbate peroxidase T, chloroplastic | CCAS2499.b1 | Q42593 | 2.00E-18 | Ascorbate peroxidase activity |
| Glutathione reductase | CCAS6616.g1 | P30635 | 7.00E-30 | Generation of reduced glutathione |
| Glutamate-cysteine ligase catalytic subunit | CCAS1277.g1 | P19468 | 3.00E-80 | |
| Glutathione synthetase | Contig25 | P35668 | 3.00E-60 | Synthesis of glutathione |
| Glutathione transferase omega-like | Contig320 | Q04806 | 7.00E-21 | |
| Gamma-glutamyltranspeptidase | Contig586 | P18956 | 1.00E-42 | Extracellular glutathione breakdown |
| Apoptosis-/Autophagy-related | ||||
| Apoptosis inhibitor 1 | Contig462 | Q24306 | 1.00E-08 | |
| Apoptosis inhibitor 2 | CCAS3883.b1 | P41454 | 3.00E-10 | |
| Apoptosis-inducing factor 1 | CCAS6130.g1 | O95831 | 9.00E-57 | |
| Apoptosis-inducing factor 2 | CCAS2159.g2 | Q8BUE4 | 2.00E-38 | |
| Caspase-3 | CCAS2871.b1 | Q2PFV2 | 5.00E-11 | Effector caspase |
| Caspase-8 | Contig694 | O89110 | 3.00E-08 | Initiator caspase |
| Caspase-10 | CCAS4895.g1 | Q92851 | 3.00E-09 | Initiator caspase |
| Histone-lysine N-methyltransferase HRX | Contig595 | Q03164 | 7.00E-31 | Promotes PPP1R15A-induced apoptosis |
| Death-associated protein kinase 3 | Contig472 | O88764 | 9.00E-10 | Positive regulator of apoptosis |
| Large proline-rich protein BAT3 | CCAS4314.b1 | Q9Z1R2 | 1.00E-18 | Role in ricin-induced apoptosis |
| Autophagy-related protein 7 | CCAS4000.g1 | Q641Y5 | 1.00E-93 | |
| Autophagy-related protein 23 | CCAS4265.g1 | Q6BHF8 | 5.00E-06 | |
| Damage-regulated autophagy modulator | CCAS6260.g1 | Q5EAK8 | 1.00E-12 | |
| Endo-, Exo-, Phagocytosis-related | ||||
| Ankyrin-1 | CCAS3968.g1 | P16157 | 2.00E-26 | Attach membrane proteins to cytoskeleton |
| AP-1 complex subunit beta-1 | CCAS4406.g1 | Q10567 | 5.00E-58 | Clathrin-associated adaptor protein complex 1 |
| Dynamin-1 | CCAS5621.g1 | P21575 | 7.00E-69 | Vesicular trafficking processes |
| Exocyst complex component 6 | Contig181 | Q8TAG9 | 2.00E-21 | Component of the exocyst complex |
| Formin-binding protein 1 | CCAS4356.g1 | Q96RU3 | 1.00E-09 | Membrane tubulation |
| Intersectin-1 | CCAS6126.g1 | Q9Z0R4 | 4.00E-12 | Formation of clathrin-coated vesicles |
| SNARE-interacting protein KEULE | Contig601 | Q9C5X3 | 5.00E-15 | Vesicle trafficking in cytokinesis |
| Ras-related protein ARA-5 | Contig1350 | P28188 | 2.00E-30 | Homolog to Rab7 |
| Immunity-related | ||||
| Complement C2 | Contig732 | Q3SYW2 | 2.00E-19 | |
| Complement C3 | CCAS2220.b1 | P23667 | 5.00E-10 | |
| Complement C5 | CCAS2793.b1 | P06684 | 6.00E-11 | |
| Complement component C8 beta chain | CCAS2550.g1 | P07358 | 3.00E-08 | |
| NF-kappa-B inhibitor alpha | CCAS395.g1 | P25963 | 2.00E-21 | |
| Heat-shock-related | ||||
| DnaJ homolog subfamily B member 4 | CCAS6247.g1 | Q9UDY4 | 7.00E-45 | |
| DnaJ homolog subfamily C member 10 | Contig808 | Q9DC23 | 1.00E-27 | |
| DnaJ homolog subfamily C member 13 | Contig104 | O75165 | 7.00E-07 | |
| DnaJ homolog subfamily C member 21 | CCAS2838.g1 | Q6PGY5 | 3.00E-56 | |
| DnaJ homolog subfamily C member 7 | Contig1270 | Q9QYI3 | 8.00E-42 | |
| Heat shock 70 kDa protein | Contig753 | P41753 | 2.00E-62 | |
| Heat shock 70 kDa protein 1B | Contig573 | Q27965 | 1.00E-170 | |
| Heat shock 70 kDa protein 2 | Contig906 | P18694 | 1.00E-12 | |
| Heat shock 70 kDa protein 4 | CCAS4411.b1 | Q2TFN9 | 2.00E-22 | |
| Heat shock 70 kDa protein C | Contig926 | P19208 | 6.00E-12 | |
| Heat shock cognate 71 kDa protein | Contig1309 | Q71U34 | 0 | |
| Heat shock factor protein | Contig401 | P41154 | 1.00E-57 | |
| Heat shock protein 81-1 | CCAS3866.g1 | P27323 | 9.00E-61 | |
| Heat shock protein 83 | CCAS3866.b1 | P02828 | 5.00E-20 | |
| Heat shock protein 90 | Contig1047 | O44001 | 6.00E-52 | |
| Heat shock protein homolog SSE1 | CCAS4411.g1 | Q875V0 | 7.00E-44 | |
| Heat shock protein HSP 90-alpha | Contig636 | O02705 | 4.00E-29 | |
| Heat shock protein HSP 90-beta | Contig968 | Q76LV1 | 1.00E-180 | |
| Glycan/Lectin-related | ||||
| Calreticulin | CCAS6359.b1 | P27798 | 1.00E-11 | Lectin |
| C-type lectin domain family 4 member F | Contig203 | P10716 | 4.00E-20 | Receptor; affinity for galactose/fucose |
| Ficolin-1 | CCAS2736.b1 | Q9WTS8 | 7.00E-13 | Binds GlcNAc |
| Ficolin-2 | CCAS3003.b1 | Q29041 | 2.00E-58 | Binds GlcNAc |
| Fucolectin-1 | Contig1154 | Q9I931 | 2.00E-13 | Binds fucose |
| Fucolectin-4 | CCAS2219.g1 | Q9I928 | 3.00E-12 | Binds fucose |