Table 3.
Effect of venous thromboembolism (VTE) on survival of patients with different cancer types, stratified by initial Surveillance, Epidemiology and End Results (SEER) cancer stage, and adjusted for age, race and gender.
| Hazard ratio for death within 1 year among cases with VTE diagnosed in Year 1 vs no VTE (95% confidence interval), adjusted for age, race and gender | |||
|---|---|---|---|
| Cancer type | Initial stage | ||
| Local | Regional | Metastatic | |
| Prostate | 5.6 (3.8–8.5)§ | 4.7 (1.9–11.5)§ | 2.8 (1.5–5.0)† |
| Breast | 6.6 (3.7–11.8)§ | 2.4 (1.3–4.5)† | 1.8 (1.1–2.9)* |
| Lung | 3.1 (2.1–4.5)§ | 2.9 (2.3–3.5)§ | 2.5 (2.3–2.7)§ |
| Colon/rectum | 3.2 (1.8–5.5)§ | 2.2 (1.7–3.0)§ | 2.0 (1.7–2.4)§ |
| Melanoma | 14.4 (4.6–45.2)§ | N/A | 2.8 (1.5–5.3)† |
| Non-Hodgkin’s lymphoma | 3.2 (1.9–5.3)§ | 2.0 (1.3–3.2)† | 2.3 (1.7–3.1)§ |
| Uterus | 7.0 (3.4–14.2)§ | 9.1 (4.8–17.2)§ | 1.7 (1.0–3.0)* |
| Bladder | 3.2 (1.7–6.2)§ | 3.3 (1.7–6.4)§ | 3.3 (1.8–6.2)§ |
| Pancreas | 2.3 (1.2–4.6)* | 3.8 (2.8–5.1)§ | 2.3 (1.9–2.7)§ |
| Stomach | 2.4 (1.1–5.1)* | 1.5 (1.0–2.1)* | 1.8 (1.4–2.3)§ |
| Ovary | 11.3 (2.5–51.7)† | 4.8 (1.1–20.4)* | 2.3 (1.7–3.0)§ |
| Kidney | 3.2 (1.2–8.8)* | 1.4 (0.6–3.2) | 1.3 (0.9–2.0) |
Note: VTE was modelled as a time-dependent covariate.
N/A = Not enough VTE cases to estimate.
P<0.05.
P<0.01.
P<0.001.