Table 1.

Summary of overlap between A2.1-restricted VACV T cell epitope recognition in HLA Tg mice and human systems

Epitope	Sequence	Original Identification	Reference	Average Net SFC/106 Cells
				Tg Mice	Human
A6L172–180	ILSDENYLL	Human	[9]	-	106
A26L177–186	YLYTEYFLFL	Human	[9]	-	164
A36R1–9	MMLVPLITV	Human	[9]	75	49
A55R78–86	YIYGIPLSL	Human	[9]	-	94
D3R342–350	FLVIAINAM	Human	[9]	-	195
E2L249–257	KIDYYIPYV	Human	[9]	87	192
E9L107–115	FLNISWFYI	Human	[9]	48	132
F12L286–295	NLFDIPLLTV	Human	[9]	132	252
F12L404–412	FLTSVINRV	Human	[9]	90	73
I4L720–728	SMHFYGWSL	Human	[9]	-	102
N2L93–101	YVNAILYQI	Human	[9]	-	563
O1L247–255	GLNDYLHSV	Human	[9]	104	77
C7L74–82	KVDDTFYYV	Human + Tg mice	[5,9,14,15,18]	100	178
G5R18–26	ILDDNLYKV	Human + Tg mice	[5,9,14]	141	271
A6L6–14	VLYDEFVTI	Tg mice	[5]	126	-
A14L51–59	FILGIIITV	Tg mice	[5]	844	60
A17L61–70	RTLLGLILFV	Tg mice	[5]	279	-
A17L81–90	ILMIFISSFL	Tg mice	[5]	773	42
A17L138–146	QIFNIISYI	Tg mice	[13]	231	-
A46R142–150	GLFDFVNFV	Tg mice	[5]	202	-
B6R108–116	LMYDIINSV	Tg mice	[5]	222	-
B14R327–335	HVDGKILFV	Tg mice	[5]	137	-
D12L251–259	RVYEALYYV	Tg mice	[5]	112	63
F11L196–204	FLIVSLCPT	Tg mice	[5]	150	-
G7L250–258	YLPEVISTI	Tg mice	[5]	86	-
H3L184–192	SLSAYIIRV	Tg mice	[5,16]	213	-
I1L211–219	RLYDYFTRV	Tg mice	[5]	179	115
M1L374–383	IIIPFIAYFV	Tg mice	[5]	840	91