Table 2.
Results of the univariate and multivariate analysis of the characteristics of tuberculosis (TB) patients associated with death during anti-TB treatment, Shanghai, 2000–2004
| Characteristics | Survived | Died | OR | (95% CI) | P value | AOR | (95% CI) | P value | ||
|---|---|---|---|---|---|---|---|---|---|---|
| No. | (%) | No. | (%) | |||||||
| Age (years) | ||||||||||
| 11–29 | 1034 | (13.9) | 2 | (0.5) | 1.0 | 1.0 | ||||
| 30–44 | 1624 | (21.8) | 19 | (4.3) | 6.0 | (1.5–53.6) | 0.006 | 5.0 | (1.2–21.7) | 0.031 |
| 45–59 | 1924 | (25.9) | 42 | (9.5) | 11.3 | (2.9–96.4) | <0.001 | 8.2 | (2.0–34.3) | 0.004 |
| 60–74 | 1883 | (25.3) | 174 | (39.5) | 47.8 | (13.0–398.1) | <0.001 | 35.4 | (8.7–143.6) | <0.001 |
| ≥ 75 | 968 | (13.0) | 203 | (46.1) | 108.4 | (29.5–902.7) | <0.001 | 82.3 | (20.3–333.2) | <0.001 |
| Sex | ||||||||||
| Female | 1681 | 22.6 | 55 | 12.5 | 1.0 | 1.0 | ||||
| Male | 5752 | 77.4 | 385 | 87.5 | 2.0 | (1.5–2.8) | <0.001 | 1.7 | (1.2–2.3) | 0.001 |
| Case type | ||||||||||
| New case | 6056 | 81.5 | 327 | 74.3 | 1.0 | - | ||||
| Retreatment case | 1377 | 18.5 | 113 | 25.7 | 1.5 | (1.2–1.9) | <0.001 | - | ||
| Cavity on initial chest radiograph | ||||||||||
| Absent | 4943 | 66.5 | 315 | 71.6 | 1.0 | - | ||||
| Present | 2266 | 30.5 | 110 | 25.0 | 0.8 | (0.6–0.9) | 0.016 | - | ||
| Uncertain | 224 | 3.0 | 15 | 3.4 | - | - | ||||
| Sputum Smear | ||||||||||
| Negative | 1461 | 18.6 | 1416 | 19.0 | 1.0 | 1.0 | ||||
| Positive | 6334 | 80.4 | 5945 | 80.0 | 2.1 | (1.5–2.9) | <0.001 | 1.6 | (1.2–2.2) | 0.004 |
| Unknown | 78 | 1.0 | 72 | 1.0 | - | - | ||||
| Comorbidity | ||||||||||
| Absent | 5938 | 79.9 | 293 | 66.6 | 1.0 | 1.0 | ||||
| Present | 1466 | 19.7 | 142 | 32.3 | 2.0 | (1.6–2.4) | <0.001 | 1.4 | (1.1–1.7) | 0.004 |
| Unknown | 29 | 0.4 | 5 | 1.1 | - | - | ||||
| Drug susceptibility results | ||||||||||
| Non-MDR | 4487 | 60.4 | 227 | 51.6 | 1.0 | - | ||||
| MDR | 241 | 3.2 | 15 | 3.4 | 1.2 | (0.7–2.1) | 0.450 | - | ||
| Unknown | 2705 | 36.4 | 198 | 45.0 | 1.4 | (1.2–1.8) | <0.001 | - | ||
TB = tuberculosis; OR = odds ratio; AOR = adjusted odds ratio; CI = confidence interval; MDR = multidrug resistance