Table 2.
Group statistics (BPD with PTSD v. BPD without PTSD v. controls) for hippocampus and amygdala volumes of women with borderline personality disorder with or without posttraumatic stress disorder and matched controls
| Group; mean (SD) brain volume, mm3 |
|||||
|---|---|---|---|---|---|
| Brain region | BPD with PTSD (n = 10) | BPD witho ut PTSD (n = 15) | Controls (n = 25) | MANCOVA | p value |
| Hippocampus | F2,45 = 3.512 | 0.038 | |||
| Left | 2 870 (470) | 3 160 (304) | 3 084 (393) | ||
| Right | 3 012 (488) | 3 219 (292) | 3 224 (410) | ||
| Amygdala | F2,45 = 0.246 | 0.78 | |||
| Left | 1 960 (261) | 1 910 (180) | 1 903 (284) | ||
| Right | 2 073 (287) | 1 980 (193) | 1 934 (435) | ||
| Whole brain | 1 282 756 (103 436) | 1 281 285 (83 547) | 1 252 628 (122 740) | ||
BPD = borderline personality disorder; MANCOVA = multivariate analysis of covariance; PTSD = posttraumatic stress disorder; SD = standard deviation.