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. 2009 Jan;276(2):376–386. doi: 10.1111/j.1742-4658.2008.06788.x

Fig. 2.

Fig. 2

EC50 values for methylglyoxal against the ‘Tritryp’ trypanosomatids. The EC50 values for methylglyoxal against L. major promastigotes (open squares), T. cruzi epimastigotes (open triangles) and T. brucei procyclics (closed circles) were determined. The curves are the nonlinear fits of data using a two-parameter EC50 0–100% equation provided by grafit (see Experimental procedures). EC50 values of 70 ± 2 methylglyoxal, 171 ± 11 and 397 ± 27 μm were determined for T. brucei, T. cruzi and L. major with corresponding slope factors (m) of 3.0, 1.6 and 1.59, respectively. Data are the means of triplicate measurements.