Table 1.
Demographics by Genotype, separated by SNP
| val158met SNP (rs4680) | Val/Val | Val/Met | Met/Met | All | ANOVA |
|---|---|---|---|---|---|
| Variable | (n = 38) | (n = 78) | (n = 35) | (n = 151) | p-value |
| Age | 31.1 (8.9) | 34.1 (10.4) | 32.4 (8.6) | 32.9 (9.7) | p = 0.281* |
| Gender (M/F) | 19/19 | 35/43 | 18/17 | 72/79 | p = 0.773* |
| Education years | 16.4 (3.9) | 16.8 (2.7) | 17.3 (3.2) | 16.8 (3.1) | p = 0.505* |
| WAIS full scale IQ | 108.9 (8.9) | 107.6 (8.8) | 106.1 (7.8) | 107.6 (8.6) | p = 0.373* |
| Handedness | 84.6 (44.3) | 76.4 (53.2) | 85.4 (38.6) | 80.5 (47.9) | p = 0.539* |
| P2 promoter SNP (rs2097603) | A/A | A/G | G/G | All | ANOVA |
| Variable | (n = 42) | (n = 81) | (n = 23) | (n = 146) | p-value |
| Age | 34.4 (10.6) | 31.6 (9.0) | 35.9 (10.2) | 33.1 (9.8) | p = 0.108* |
| Gender (M/F) | 20/22 | 40/41 | 9/14 | 69/77 | p = 0.689* |
| Education years | 17.0 (3.8) | 16.6 (3.0) | 17.0 (2.6) | 16.8 (3.2) | p = 0.763* |
| WAIS full scale IQ | 109.5 (9.0) | 107.0 (8.6) | 106.0 (7.9) | 107.5 (8.7) | p = 0.156* |
| Handedness | 83.6 (45.3) | 79.6 (48.2) | 84.3 (41.3) | 81.5 (46.1) | p = 0.859* |
| 3″ flanking SNP (rs737865) | A/A | A/G | G/G | All | ANOVA |
| Variable | (n = 65) | (n = 64) | (n = 13) | (n = 142) | p-value |
| Age | 33.0 (10.0) | 32.8 (9.8) | 31.6(9.3) | 32.8 (9.6) | p = 0.793* |
| Gender (M/F) | 29/36 | 34/30 | 5/8 | 68/74 | p = 0.491* |
| Education years | 16.5 (3.7) | 16.6 (3.4) | 17.8 (2.3) | 16.8 (3.2) | p = 0.400* |
| WAIS full scale IQ | 105.3 (9.1) | 106.0 (12.0) | 113.3 (6.4) | 107.4 (8.6) | p = 0.004 |
| Handedness | 86.5 (35.0) | 77.9 (50.9) | 97.7 (6.0) | 79.9 (49.1) | p = 0.059* |
Means (± SD).
*
There is no significant difference between genotype for any variable