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. Author manuscript; available in PMC: 2009 Jun 29.
Published in final edited form as: Proc West Pharmacol Soc. 2008;51:30–34.

Figure 4.

Figure 4

Compounds tested as NDPK-B inhibitors. Compound 1 = PAPS (adenosine 3’-phosphate 5’-phosphosulfate); 2 = theaflavin; 3 = theaflavin gallate; 4 = EGCG (epigallocatechin gallate; 5 = EGC (epigallocatechin; 6 = ECG (epicatichingallate); 7 = ellagic acid. Compounds numbered in blue (3–6) contain a gallate group as delimited by the red box. For all the polyphenols tested, the presence of the gallate group correlates with inhibition of NDPK. Compounds 1, 2 and 7 are not gallates. Ellagic acid (compound 7) is not a gallate but has a related structure and a symmetry that may improve binding to the enzyme.