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. 2009 Jul 8;4(7):e6052. doi: 10.1371/journal.pone.0006052

Table 2. Spearman correlation coefficient between the PLM and ALM frequency profiles.

structural classa TreeFam id UniProt id ELM id Start locCons corr globCons corr
TF106427 P29374 LIG_RB 957 −0.14 0.12
TF106496 P25054 TRG_NES_CRM1_1 163 −0.09 −0.05
TF316358 P10636 LIG_SH3_1 565 −0.05 0.42
TF300785 P51531 LIG_RB 1294 −0.01 0.12
TF314303 O15147 LIG_SH3_5 389 −0.01 0.16
TF325994 P35568 LIG_14-3-3_3 267 0.12 0.29
TF331759 O60315 LIG_CtBP 785 0.16 0.20
TF323952 P17535 LIG_COP1 241 0.16 0.33
DIS DIS TF325994 P35568 LIG_14-3-3_3 371 0.29 0.42
TF318445 O35973 TRG_NES_CRM1_1 488 0.32 0.50
TF325994 P35570 LIG_SH2_GRB2 896 0.45 0.52
TF101166 P05205 LIG_RB 61 0.53 0.10
TF320471 P35712 LIG_CtBP 424 0.36 0.15
TF313876 Q91VZ6 LIG_Clathr_ClatBox_l 192 0.31 0.16
TF325994 P35570 LIG_SH2_PTP2 1179 0.23 0.21
TF331759 O60315 LIG_CtBP 859 0.34 0.31
TF323952 P05412 MOD_PIKK_l 246 0.55 0.52
TF105306 Q00987 MOD_PIKK_l 392 −0.02 0.02
DIS GLOB TF323952 P05412 LIG_MAPK_1 32 0.55 0.27
TF314861 Q05140 LIG_PIP2_ANTH_1 28 0.51 0.36
TF325994 P35570 MOD_CK2_1 96 0.48 0.39
TF335892 P04235 TRG_LysEnd_APsAcLL_l 138 0.18 0.28
TF300460 Q04656 TRG_LysEnd_APsAcLL_l 1483 0.38 0.00
TF105137 Q02750 LIG_MAPK_1 3 0.34 0.11
TF300618 P27797 TRG_ER_KDEL_l 414 0.53 0.22
GLOB DIS TF105135 P45985 LIG_MAPK_1 40 0.36 0.28
TF105115 Q99683 LIG_14-3-3_1 963 0.33 0.31
TF300540 P04040 TRG_PTS1 523 0.38 0.36
TF105044 P36604 TRG_ER_KDEL_1 660 0.45 0.42
TF106381 P09103 TRG_ER_KDEL_l 506 0.52 0.48
TF105042 P17156 LIG_TPR 630 0.65 0.52
TF335892 P19377 MOD_TYR_ITAM 146 −0.05 −0.08
TF101211 Q8AY27 MOD_PIKK_l 2 0.03 0.00
TF101004 P24385 LIG_RB 5 0.22 0.10
GLOB GLOB TF105115 Q99683 LIG_RB 916 0.19 0.17
TF105122 P28562 LIG_MAPK_2 339 0.44 0.25
TF315491 P27918 MOD_CMANNOS 318 0.37 0.27
TF105331 Q96GD4 LIG_APCC_Dbox_l 314 0.65 0.53
TF316520 O00268 LIG_HP1_1 762 −0.07 0.01
TF101065 Q12834 LIG_APCC_KENbox_2 96 −0.01 0.04
TF313542 P49418 LIG_AP2alpha_l 324 0.03 0.15
TF300772 P49736 MOD_PIKK_1 105 0.09 0.16
MIXED DIS TF105351 P35465 LIG_SH3_2 13 0.11 −0.06
TF332149 O75074 TRG_LysEnd_GGAAcLL_l 764 0.35 0.01
TF106101 P04637 TRG_NES_CRM1_1 339 0.04 0.01
TF318574 Q9UJY5 TRG_LysEnd_GGAAcLL_2 355 0.34 0.03
TF101089 P53350 LIG_APCC_Dbox_l 336 0.33 0.14
TF105722 P35251 LIG_RB 662 −0.11 −0.06
TF300901 P23396 LIG_MAPK_2 77 0.24 0.41
MIXED GLOB TF333209 P54274 MOD_PIKK_1 216 −0.08 −0.10
TF318283 P46061 MOD_SUMO 525 0.10 −0.07
TF101066 Q8UWJ8 LIG_CYCLIN_l 445 0.31 0.19
TF330851 P10912 LIG_SH2_STATB 566 0.30 0.21

Spearman correlation coefficient calculated between the PLM and ALM frequency profiles of each instance. Correlation of the frequency profiles of IU Pdiff versus locCons and IU Pdiff versus globCons are indicated as locCons corr and globCons corr respectively. Correlation of 1 would indicate that the PLM and ALM sets cover the same IU Pdiff and locCons/globCons ranges. A correlation of −1 would imply that those ranges are completely disjoint and diametrically opposed (e.g. high IU Pdiff and low locCons for ALM while low IU Pdiff and high locCons for PLM). Small positive or negative values indicate that the ranges tend to be disjoint but not opposite. Instances in bold have PLM and ALM sets with significantly different IU Pdiff distributions (p-values<0.05).

a

protein and module structural classes.