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Metalloid uptake of L. donovani cells expressing wild-type or altered LmAQP1. Panels A and B depict As(III) uptake in L. donovani promastigotes and amastigotes, respectively; Panels C and D represent Sb(III) uptake in L. donovani promastigotes and amastigotes, respectively. Cells were transfected with wild-type, E143A/E145A, E152A, E152D, E152Q LmAQP1 or vector control.
