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. Author manuscript; available in PMC: 2009 Sep 11.
Published in final edited form as: Oncogene. 2008 May 26;27(40):5373–5384. doi: 10.1038/onc.2008.155

Figure 5.

Figure 5

Downregulation of TNC in MDA-MB-435 cells reduces the number of lung metastatic foci. (a) Metastatic nodule (arrow) in the lung of a mouse injected with shCtrl cells. (b) Quantification of the number of lung metastatic foci. The average number of metastatic nudules was lower in animals injected with shTNC-3 cell clones than in mice injected with shCtrl cells (P < 0.05). No statistically significant differences were found when comparing data from shTNC-1 and shTNC-3 cells with parental cells or when comparing data from shTNC-1 with the shCtrl group (*P = 0.05 for the latter comparison).