Table 1.
Tissue colonization |
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Y. pestis dose (no. CFU) | Bacteremia | Lung | TBLN | Spleen | Liver | Gram stain of pulmonary tissue |
12 | – | – | – | – | – | – |
16 | – | – | – | – | – | – |
35 | + (3, 4) | ++ | ++ | ++ | + | ++ |
58 | ++++ | – | – | – | – | – |
122 | + (6, 7) | + | ++ | + | + | ++++ |
169 | +++ | +++ | ++ | ++ | ++ | ++ |
174 | – | – | – | – | – | +++ |
198 | – | – | – | – | – | – |
208 | + (3, 4) | ++ | ++ | + | + | +++ |
227 | – | – | – | – | – | – |
262 | + (5, 6) | +++ | ++ | + | ++ | ND |
264 | + (6, 7) | +++ | ++ | ++ | ++ | ND |
295 | + (4, 5) | ++++ | ++++ | ++ | +++ | ND |
353 | +++ | ++++ | +++ | +++ | +++ | ND |
374 | ++++ | ++++ | ++ | ++ | ++ | ND |
479 | – | +++ | ++ | – | + | ND |
759 | – | +++ | ++ | – | – | ND |
3050 | ++++ | ++++ | ++++ | ++++ | ++++ | ND |
4410 | + (4, 7) | +++ | + | + | + | ND |
4850 | ++++ | ++++ | ++++ | ++++ | ++++ | ND |
12400 | + (3, 4) | ND | ND | ND | ND | ND |
42700 | +++ | ND | ND | ND | ND | ND |
–, no growth; + = 1 to 100 CFU; ++ = 101 to 1000 CFU; +++ = 1001 to 100,000 CFU; ++++ = more than 100,000 CFU); ND, not done; TBLN, tracheobronchiolar lymph nodes.
Days on which bacteremia was seen are noted in parentheses.