Table 1.
Qualitative analysis of Y. pestis bacteremiaa from samples taken daily on days 1 to 7 postinoculation or by semiquantitative analysis of tissue colonization after euthanasia
| Tissue colonization |
||||||
| Y. pestis dose (no. CFU) | Bacteremia | Lung | TBLN | Spleen | Liver | Gram stain of pulmonary tissue |
| 12 | – | – | – | – | – | – |
| 16 | – | – | – | – | – | – |
| 35 | + (3, 4) | ++ | ++ | ++ | + | ++ |
| 58 | ++++ | – | – | – | – | – |
| 122 | + (6, 7) | + | ++ | + | + | ++++ |
| 169 | +++ | +++ | ++ | ++ | ++ | ++ |
| 174 | – | – | – | – | – | +++ |
| 198 | – | – | – | – | – | – |
| 208 | + (3, 4) | ++ | ++ | + | + | +++ |
| 227 | – | – | – | – | – | – |
| 262 | + (5, 6) | +++ | ++ | + | ++ | ND |
| 264 | + (6, 7) | +++ | ++ | ++ | ++ | ND |
| 295 | + (4, 5) | ++++ | ++++ | ++ | +++ | ND |
| 353 | +++ | ++++ | +++ | +++ | +++ | ND |
| 374 | ++++ | ++++ | ++ | ++ | ++ | ND |
| 479 | – | +++ | ++ | – | + | ND |
| 759 | – | +++ | ++ | – | – | ND |
| 3050 | ++++ | ++++ | ++++ | ++++ | ++++ | ND |
| 4410 | + (4, 7) | +++ | + | + | + | ND |
| 4850 | ++++ | ++++ | ++++ | ++++ | ++++ | ND |
| 12400 | + (3, 4) | ND | ND | ND | ND | ND |
| 42700 | +++ | ND | ND | ND | ND | ND |
–, no growth; + = 1 to 100 CFU; ++ = 101 to 1000 CFU; +++ = 1001 to 100,000 CFU; ++++ = more than 100,000 CFU); ND, not done; TBLN, tracheobronchiolar lymph nodes.
a
Days on which bacteremia was seen are noted in parentheses.