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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Structure. 2009 Apr 15;17(4):530–537. doi: 10.1016/j.str.2009.02.015

Figure 1.

Figure 1

Polι Abasic.dNTP ternary complexes and corresponding simulated annealed omit maps of the incipient “base pairs”. A) Polι Abasic.dGTP ternary complex (left), shown for one of the two Polι molecules bound to a double-ended template primer. The palm, fingers, thumb domain and the PAD in the Polι molecule are shown in cyan, yellow, orange and green respectively. DNA is shown in gray, abasic lesion and incoming dGTP are in red, and the putative Mg2+ ions are displayed as dark blue spheres. The simulated annealing Fo-Fc omit map (contoured at 3.0σ) for the abasic lesion and incoming dGTP is shown on right. B) Polι Abasic.dTTP ternary complex and corresponding simulated annealing Fo-Fc omit map. C) Polι Abasic.dATP ternary complex and corresponding simulated annealing Fo-Fc omit map.