Relative survival (3 and 5-year) for localized RCC greater than 7 cm by age group. RS rates represent comparison of observed survival in patients with large (greater than 7 cm) tumors to expected survival for age, sex and race matched cancer-free population. Therefore, likelihood of 5-year survival for 38-year-old patient treated surgically for large localized RCC is less than that of age, sex and race matched control without cancer (87.4%). Similarly elderly patients with large, surgically treated, localized RCC demonstrate reduced overall survival compared to peers without cancer. Comparisons of RS rates among age cohorts revealed no statistically significant differences, suggesting that large tumor size decreases relative survival equally across all age groups.