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Tail cuff systolic blood pressure (A) and heart rate (B) were recorded among AA (■, N = 15 males and 14 females), RA (▨, N = 6 males and 6 females) and RR (□, N = 7 males and 6 females) mice. To measure generalized anxiety, these mice were then placed into a 40.6 × 40.6 cm open-field and infrared beam breaks were recorded for 5 minutes (C). Beam breaks into the center were normalized by total activity (D). *p<0.05 and ** p<0.01 versus AA
