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Plasma gonadotropin levels in GnRHR-TAg transgenic (T) (black bars) mice measured by RIA. Circulating LH levels in 2- and 5-month female (A) and male (B) mice, and FSH levels in female (C) and male (D) mice at 2 and 5 months, measured by RIA. Data are presented as mean ± sem. *, P < 0.05 vs. nontransgenic (NT) (white bars) littermate controls at the same age; **, P < 0.05 vs. transgenic female mice at 2 months of age.
