Table 2. Summary of test data and quality of σ(z) estimation.
For each entry, the data appearing in the columns are the Protein Data Bank identifier of the target structure, the resolution of the target map, the standard deviation of the actual z-statistics, the estimate of the standard deviation of the z-statistics calculated according to (5), an accuracy measure for this estimate, the mean correlation coefficient between target map and search structure, the mixing factor between Gaussian noise and Laplacian impulse noise (1.0 corresponds to Gaussian only, 0.0 to Laplacian only) and a measure of the extent of voxel correlation (the relative weight for neighboring voxels in respect to the central voxel).
PDB code | Resolution (Å) | σ(z)true | σ(z)est | Accuracy | CC | Mix | Weight |
---|---|---|---|---|---|---|---|
1oao | 6 | 0.00753 | 0.00771 | 0.0922 | 0.8693 | 0.5 | 0.08 |
15 | 0.01087 | 0.01219 | 0.4097 | 0.9419 | 0.8 | 0.12 | |
25 | 0.02498 | 0.01644 | 1.1337 | 0.8649 | 0.7 | 0.17 | |
1lfh | 15 | 0.00959 | 0.00964 | 0.0207 | 0.9883 | 0.5 | 0.08 |
20 | 0.01239 | 0.01112 | 0.3889 | 0.9435 | 0.8 | 0.13 | |
20† | 0.01066 | 0.01112 | 0.1620 | 0.9108 | 0.8 | 0.13 | |
1hwz | 10 | 0.00978 | 0.01261 | 0.7970 | 0.9390 | 0.5 | 0.20 |
15 | 0.01071 | 0.01489 | 0.9653 | 0.8243 | 0.9 | 0.14 | |
20 | 0.02124 | 0.01735 | 0.6655 | 0.6450 | 0.6 | 0.07 | |
1blb | 10 | 0.01567 | 0.01967 | 0.7307 | 0.6239 | 0.6 | 0.25 |
12 | 0.02191 | 0.02155 | 0.0652 | 0.5619 | 0.3 | 0.08 | |
15 | 0.03031 | 0.02409 | 0.7366 | 0.4842 | 0.8 | 0.13 |
Rigid-body docking with the entire unmodified search structure was used.