Table 3.

Survival analyses estimating hazard ratios (and 95% confidence intervals) for adult onset arthritis with stratification by country. [All models control for sex and current age and are stratified by country].

	Childhood adversities				Early onset mood-anxiety disorder		Current mood-anxiety disorder
	None	One	Two	Three or More	Absent	Present	Absent	Present
Model One: Effect of childhood adversities without controlling for mood/anxiety disorder	1.00	1.02 [.89,1.16]	1.31 [1.12,1.54]	1.53 [1.31,1.78]
Model Two: Effect of childhood adversities controlling for current mood/anxiety disorder	1.00	1.01 [.88,1.15]	1.28 [1.09,1.50]	1.43 [1.24,1.60]			1.00	1.43 [1.29,1.57]
Model Three: Effect of childhood adversities and early onset mood/anxiety disorder	1.00	1.00 [.88,1.14]	1.27 [1.08,1.50]	1.44 [1.24,1.67]	1.00	1.43 [1.28,1.61]
Model Four: Effect of early onset mood/anxiety disorder without controlling for childhood adversities					1.00	1.52 [1.36,1.70]

Notes: Interaction of early onset mood disorder and presence of multiple childhood adversities was non-significant.