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Schematic representation of WT and mutant forms of rat SH2B1β used in the study. Actin-binding domains (amino acids 150–200 and 615–670) are shown in gray. PH is the PH domain (amino acids 274–376), and SH2 is the SH2 domain (amino acids 527–620). Proline-rich regions (amino acids 13–24, 89–103, and 469–496), and dimerization domain (amino acids 24–85) are not shown.
