Table 1.
Test group 1 particle gradient compared to background after a single actuation of BDP-HFA PMDI: decrease in submicrometric and increase in larger particle number in the presence of ETS.
| Particle diameter | 0.3–1.0 μm | 1.1–2.0 μm | 2.1–3.0 μm | 3.1–4.0 μm | 4.1–5.0 μm | > 5.1 μm |
| Ambient Air | ||||||
| Test # 1 | 19538 ± 2373 | 1421 ± 251 | 632 ± 162 | 58 ± 45 | 17 ± 35 | 12 ± 45 |
| Test # 2 | 19759 ± 1355 | 1343 ± 191 | 504 ± 107 | 21 ± 46 | 11 ± 30 | 30 ± 42 |
| Test # 3 | 18536 ± 849 | 1505 ± 178 | 643 ± 128 | 38 ± 41 | 25 ± 30 | 20 ± 42 |
| Pooled data of 3 tests | 19277 ± 2292 | 1423 ± 249 | 593 ± 156 | 39 ± 45 | 18 ± 32 | 21 ± 43 |
| ETS | ||||||
| Test # 4 | -4430 ± 4895 | 4523 ± 1186 | 1968 ± 668 | 108 ± 67 | 25 ± 38 | 9 ± 40 |
| Test # 5 | -3941 ± 5193 | 4655 ± 1228 | 2039 ± 741 | 106 ± 72 | 24 ± 41 | 16 ± 49 |
| Test # 6 | -3389 ± 5481 | 4546 ± 9367 | 2412 ± 4375 | 103 ± 172 | 40 ± 52 | 26 ± 38 |
| Pooled data of 3 tests | -3920 ± 5330* | 4575 ± 5522* | 2140 ± 2584* | 106 ± 115* | 30 ± 44* | 17 ± 43 |
ETS = Environmental Tobacco Smoke; BDP-HFA pMDI = beclomethasone-hydrofluoralkane pressurized metered dose inhaler; μm = micrometers.
Values are number of particles/liter (mean ± SD).
*P < 0.001 as compared to pooled data in clean air for the same particle diameter.