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. Author manuscript; available in PMC: 2009 Jun 29.
Published in final edited form as: Circulation. 2009 Feb 23;119(9):1220–1230. doi: 10.1161/CIRCULATIONAHA.108.794834

Figure 4.

Figure 4

IK and its underlying subunit mRNA and protein expression in control, DHF, and CRT hearts. A, Representative current traces from control, DHF, and CRT myocytes elicited by voltage-clamp protocol shown in the inset. B, Current-voltage relationship of the tail current of IK (IK tail) fitted to the Boltzmann equation: IK,tail=1/{1+exp[(V1/2-Vm)/k]}. Voltage-clamp protocol is shown in the inset. C, IK tail density at 40 mV between anterior and lateral myocytes in each group. D through H, KvLQT1, minK, and ERG mRNA and protein expression in mid myocardium of control, DHF, and CRT dogs. A or ANT indicates anterior; L or LTR, lateral; and CSQ, calsequestrin. †P<0.05 vs control; #P<0.05 vs DHF.