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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2009 Apr 17;47(2):275–287. doi: 10.1016/j.yjmcc.2009.04.005

Figure 2. Hyperbaric oxygenation and myocardial pO2, in vivo.

Figure 2

(A) The HBO protocol used 5-min compression, 90-min maintenance of hyperbaric oxygenation (100% O2 at 2 ATA), followed by 5-min decompression using a custom-built small-animal chamber. (B) Myocardial pO2 in (non-infarcted and infarct) rat hearts measured before (normoxia) and after HBO. Data represent mean±SD obtained from 4 rats. The results show an increase in oxygenation levels reaching significance at 60 min followed by returning to baseline in about 2.5 hours in the non-infarcted hearts. In the infarcted hearts the oxygenation levels are significantly higher up to 2 hours post-treatment. It is interesting to note that a 5.8-fold increase in oxygenation is achieved in the infarct hearts after 90 min of HBO.