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. Author manuscript; available in PMC: 2009 Jun 30.
Published in final edited form as: Clin Trials. 2008;5(2):157–167. doi: 10.1177/1740774508089459

Table 1 .

Interim and final data on key outcome measures from the VALUE Trial evaluating Valsartan and Amlodipine. The randomization to the two regimens was 1:1

Hypertensive patients at high cardiovascular risk

May’98 to August’00 n=15,290 May’98 to December’03 n=15,245
Valsartan/Amlodipine Valsartan/Amlodipine
Outcome measure Events RR Events RR
All deaths 178/141 1.25 841/818 1.02
All myocardial infarctions 102/76 1.33 369/313 1.17
All strokes 124/92 1.34 322/281 1.14
Hospitalization for heart failure 104/112 0.92 354/400 0.88
New onset diabetes No data 690/845 0.81