Table 3.
HIV with Nvp resistance mutations |
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Patient | Study site | HIV subtype | Interval between single-dose Nvp and sampling, months | CD4+ cell count, cells/mm3 | HIV-1 RNA load, copies/mL | Detected in plasma | Detected in latent reservoir | Identified in plasma before current study |
LT1003 | Uganda | D | 37.5 | 336 | 129,546 | None | G190A | Not determined |
LT1020 | Uganda | D | 23.2 | 309 | 244,545 | K103N | K103N, G190A | Not determined |
LT2009 | South Africa | C | 15.3 | 286 | 219,064 | None | K103N | K103N |
LT2028 | South Africa | D | 32.0 | 205 | 14,280 | None | K103N | K103N |
LT2049 | South Africa | C | 25.6 | 291 | 32,339 | K103N | None | None |