Table 5.

Accuracy of Clinical Scoring Systems

Scoring System (Score Cutoff) by Source	Sensitivity	Specificity	Positive Likelihood Ratio (95% Confidence Interval)	Negative Likelihood Ratio (95% Confidence Interval)
Alvarado/MANTRELS
Summary of level 3 studies (≥7)			4.0 (3.2-4.9)	0.20 (0.09-0.41)
Schneider et al,36 2007 (≥7)	0.72	0.81	3.8 (3.0-4.7)	0.40 (0.27-0.43)
Owen et al,57 1992 (≥7)	0.93	0.82	5.0 (2.3-11)	0.09 (0.03-0.26)
Bond et al,42 1990
≥7			3.1 (2.2-4.5)a
6			0.29 (0.12-0.73)a
5			0.31 (0.12-0.80)a
≤4			0.05 (0-0.85)a
Modified Alvarado
Macklin et al,50 1997 (≥7)	0.76	0.79	3.6 (2.3-5.7)	0.30 (0.17-0.54)
Pediatric Appendicitis Score
Schneider et al,36 2007 (≥6)	0.82	0.65	2.4 (2.0-2.8)	0.27 (0.20-0.37)
Kharbanda logistic score
Kharbanda et al,37 2005 (>5)	0.96	0.36	1.5 (1.3-1.7)	0.10 (0.03-0.41)
Kharbanda recursive partitioning decision tree
Kharbanda et al,37 2005 (“high risk”)	0.98	0.32	1.4 (1.3-1.6)	0.06 (0.01-0.41)
Lintula appendicitis score
Lintula et al,48 2005
≥21			12 (4.3-32.0)a
16-20			1.2 (0.56-2.6)a
≤15			0.20 (0.08-0.50)a
Modified Lindberg
Dado et al,40 2000 (≥−2)	0.65	0.92	7.6 (3.0-19.6)	0.39 (0.31-0.49)

^aStratum-specific likelihood ratios.