Table 2.
Metabolic measures in newly diagnosed, antipsychotic-naïve individuals with non-affective psychosis and the control group
| Psychosis group (n=50) | Control group (n=50) | Statistics | P | |
|---|---|---|---|---|
| Fasting glucose | ||||
| mmol/l, mean (s.d.) | 4.55 (0.66) | 4.65 (0.38) | t=-1.015 | 0.313 |
| mg/dl, mean (s.d.) | 83 (12.1) | 84 (6.9) | ||
| Fasting insulin, mU/l: mean (s.d.) | 10.3 (7.3) | 9.6 (3.8) | t=0.644 | 0.576 |
| % glycosylated haemoglobin, mean (s.d.) | 4.4 (0.38) | 4.5 (0.29) | t=-1.298 | 0.197 |
| HOMA-%B, mean (s.d.) | 145.3 (44.5) | 136.5 (32.1) | t=1.014 | 0.262 |
| HOMA-%S, mean (s.d.) | 88.9 (45.0) | 81.3 (28.7) | t=1.014 | 0.313 |
| Insulin resistance, mean (s.d.) | 1.48 (1.08) | 1.40 (0.56) | t=0.509 | 0.612 |
| 2h glucose | ||||
| mmol/l, mean (s.d.) | 6.10 (1.93) | 4.49 (1.06) | t=5.148 | <0.001 |
| mg/dl, mean (s.d.) | 111 (35.2) | 82 (19.3) | ||
| Impaired glucose tolerance or diabetes, % | 16 | 0 | χ2=8.696 | 0.003 |
| Cortisol, mg/dl: mean (s.d.) | 19.0 (4.98) | 20.2 (4.57) | t=-1.269 | 0.208 |
| Interleukin-6, g/ml: mean (s.d.) | 3.63 (6.91) | 1.02 (2.10) | t=2.548 | 0.012 |
| C-reactive protein, mg/l: mean (s.d.) | 0.21 (0.28) | 0.20 (0.18) | t=0.209 | 0.835 |
| Adiponectin,a mg/dl: mean (s.d.) | 12.1 (5.9) | 12.9 (5.6) | t=-0.627 | 0.533 |
HOMA-%B, homoeostatic model assessments of steady state beta-cell function; HOMA-%S, homoeostatic model assessments of insulin sensitivity.
a. Adiponectin levels were recorded for 39 people in the psychosis group and 48 in the control group.