Table 4.

Relationship between methylation status of MINT loci and TRGs

Biomarker	Comparison	P*
MINT17	MINT31	0.033
	TFPI2	0.014
	WIF1	0.002
	SOCS1	0.013
	GATA4	NS
	RASSF1A	NS
	RARβ2	NS
MINT31	TFPI2	0.002
	WIF1	0.009
	SOCS1	0.002
	GATA 4	<0.0001
	RASSF1A	0.002
	RARβ2	0.042
TFPI2	WIF1	<0.0001
	SOCS1	0.0003
	GATA4	0.0001
	RASSF1A	<0.0001
	RARβ2	0.008
WIF1	SOCS1	0.001
	GATA4	0.002
	RASSF1A	0.0001
	RARβ2	0.005
SOCS1	GATA4	NS
	RASSF1A	0.023
	RARβ2	NS
GATA4	RASSF1A	<0.0001
	RARβ2	0.005
RASSF1A	RARβ2	NS

^*Two-tailed χ² test. All significant relationships are positive. NS, not significant.