Table 1. Infection with metacyclic L. major parasites results in significantly higher arginase activity in the lesions of BALB/c mice than CBA mice.
Arginase activity (mU/mg protein) | BALB/c | CBA |
Day 7 | 1,521.8±89.2 | 452.1±23.9 |
Day 28 | 452,363.0±22,421.3 | 221.9±9.5 |
Day 42 | 426,978.6±19,125.3 | 198.6±5.6 |
Groups of BALB/c and CBA (n = 4) mice were infected with metacyclic L. major parasites in one hind footpad and 1, 4 and 6 weeks post infection, individual footpads were harvested and arginase activity was determined by enzymatic assay. Values given are the average arginase activity ±standard deviation. Data show the results of one representative experiment out of three independent experiments.