Table 2.
Pathologic features of ICC patients with and without positive AFP
|
AFP |
|||
| + (n = 32) | - (n = 99) | P value | |
| Tumor location (%) | NS | ||
| Right lobe | 21 (65.6) | 57 (57.6) | |
| Left lobe | 8 (25.0) | 33 (33.3) | |
| Both lobes | 3 (9.4) | 9 (9.1) | |
| Tumor size (cm) | NS | ||
| mean ± SD | 7.97 ± 4.12 | 6.83 ± 2.98 | |
| ≤ 3 (%) | 2 (0.6) | 9 (0.9) | |
| Tumor number (%) | NS | ||
| Single | 25 (78.2) | 62 (62.7) | |
| ≥ 2 | 7 (21.8) | 37 (37.3) | |
| Liver cirrhosis (%) | 13 (40.6) | 22 (22.2) | 0.041 |
| Capsule formation (%) | 8 (25.0) | 15 (15.2) | NS |
| Histological grades (%) | NS | ||
| Well- Moderately | 21 (65.6) | 68 (68.6) | |
| Poorly | 11 (34.4) | 31 (31.4) | |
| Lymph node metastasis (%) | 5 (15.6) | 35 (35.4) | 0.035 |
| Portal invasion (%) | 1 (3.1) | 5 (5.1) | NS |
| Microvascular invasion (%) | 18 (56.2) | 62 (62.6) | NS |
| Immunohistochemical examinations | NS | ||
| Hepatocyte paraffin | 1 | 0 | 0 |
| Cytokeratin 19 (%) | 32 (100) | 99 (100) | |
NS: Not significant.