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. 2009 May 21;37(Web Server issue):W193–W201. doi: 10.1093/nar/gkp388

Table 1.

Performance comparison of MoPP with five popular motif finders on mycobacterial datasets

Regulon Consensus Size MoPPa YMF PRISM SCOPE Oligo MEME
MycoSigA-10 TATAMT 95 TAYAVT (1)b TATtrW (5) TATtAW (6) tTAcAAT (3) TANDVTgk (2) TAgACT (1) TAcAAT (2) TAgACT (1)
MycoSigA-35 TTGACW 95 cTKGAC (1) cTBGAC (3) TTGACW (6) gnhWTGACW (1) wyTTGMMW (1) TTGACT (2) TTGACT (1)
MycoSigA50bp TATAMT 95 TATACT (2) TAKACT (3) TAgWCW (14) tTAcAAT (14) ataTHDMAY (2)c TAgACT (6) TATtAT (11)
TTGACW TRACTa (1) TaKACT (3) TaGWCW (14) TWGACW (22) TTGACT (4) TTGACT (2)
MycoSigD-10 WNATGTd 6 gTTATG (1) gTTABG (4) ACATaT (15)
MycoSigD-35 GTAACG 6 gGWAWC (3) gGTAAC (2) GTAACG (1) GTAACG (1)
MycoSigH-10 SGTTS 10 tCGTT (1) gCGKT (2) SGTTar (21) cGGTT (3) cGGTT (3) gCGTT (1) cCGTT (2)
MycoSigH-35 SGGAAC 10 GGGAAt (1) GGGAAY (2) GGGAAC (1) GGGAAY (2) CGGAA (2) CGGAA (2) GGGAAC (1) GGGAAC (1)
MycoSigL-10 CGTGTC 5 CGTGTC (1) GTGTCa (5) GTGTCa (1) CGTGTC (2) GTGTCa (1)
MycoSigL-35 TGAACC 5 tTGAAC (1) bTGAAC (2) TGWACY (3) TGAACY (5) TGAAC (1) bTGAAC (1) TGAACC (1) cTGAAC (1)
mSr 1.0 0.4 0.5 0.5 0.8 0.8

aWeeder could not be compared since the background file was not available.

bPattern is highlighted in bold if it matches the consensus with not more than one mismatch and ranks among top five. Number in parenthesis indicates rank of the pattern.

cNot considered a match since ≥80% of the matching residues are degenerate nucleotides or matching with degenerate nucleotides.

dAccording to MtbRegList (www.usherbrooke.ca/vers/MtbRegList).