Table 3.

Hypoxia responsive motifs present upstream of genes^a

Sequenceb	Scorec	Gened
ccGGGGAtgAAcGTCCCCgc	11.8486	Rv1039c (PPE15)e
TgCGGGACTAcAaTCCCGgg	11.7186	Rv1811 (mgtC)
ggCGGGACTATgGTCgCGAc	11.414	Rv1552 (frdA)
gTCGGGgCggTgGTCCCCgg	11.2576	Rv0345
TTGGGGcCaTccGgCCCGgA	11.195	Rv0877
aTaGtGACaTTcGaCCCGAA	10.8046	Rv3318 (sdhA)f
aTCGGGcCgAAcGTCaCGAt	10.761	Rv1824
cTCGGGACaTTAcTtCCGtt	10.7435	Rv1881c (lppE)
caCGGGACgAgcaTCCCCAg	10.7301	Rv2194 (qcrC)
cTCGGGtgTgAgGTCCCatA	10.6815	Rv2221c (glnE)
gcCaGGACgTcgGgCCCGAg	10.5356	Rv1256c (cyp130)

^aIn addition to those detected by Park et al. (13).

^bLower case characters show disagreement to motif consensus.

^cCalculated as mentioned in Park et al. (13).

^dAccording to Cole et al. (36).

^eInduced in artificial granulomas (30).

^fRepressed in hypoxia in M. tuberculosis H37Rv:ΔdosR (13).