Table 1.

Statistics of annotations and proteins in annotation resources of COFECO

Organisms	Proteins					Annotations
	Complex	KEGG	GO BP	GO MF	GO CC	Complexa	KEGG	GO BP	GO MF	GO CC
M. musculus	5670	5313	33 714	39 440	34 231	2118	199	3584	2320	614
S. cerevisiae	5246	1237	5147	5020	5761	8049	110	1556	1484	511
H. sapiens	4123	5507	36 780	40 115	36 594	2858	205	3082	2612	684
R. norvegicus	2957	2674	9407	10 729	9837	1850	197	2059	1858	463
G. gallus	1820	604	4379	5058	4345	1287	121	894	984	289
A. thaliana	1606	1947	19 694	25 962	13 380	619	132	1043	1240	269
D. melanogaster	1583	2216	13 862	17 892	10 666	865	135	2196	1545	439
S. pombe	899	966	3553	3429	4790	526	106	1153	1082	370
C. elegans	806	1012	9891	11651	6456	600	122	1163	969	237

^aThe numbers of annotations for complexes are the number of complexes for each genome. Among the whole 19 064 complexes, 63% have their own function annotations or complex names and 37%, which are from high-throughput co-complex data in general, do not have complex name. In this system, complex itself is used as an annotation unit representing functionally correlated group.