Table 2.
Lists of top-three keywords related to Prader–Willi syndrome
| MeSH terms | P-value |
|---|---|
| Diseases | |
| Prader–Willi syndrome | 0 |
| Angelman syndrome | 4.05 × 10−140 |
| Obesity | 6.94 × 10−128 |
| Chemicals and Drugs | |
| Human growth hormone | 5.86 × 10−68 |
| Ribonucleoproteins, small nuclear | 4.29 × 10−62 |
| Ghrelin | 1.58 × 10−50 |
| Biological Phenomena | |
| Chromosomes, human, pair 15 | 0 |
| Genomic imprinting | 2.47 × 10−131 |
| Obesity | 1.69 × 10−121 |
| Anatomy | |
| Chromosomes, human, pair 15 | 0 |
| Chromosomes, human, 13–15 | 1.25 × 10−30 |
| Adipose tissue | 3.93 × 10−13 |
We generated feature profiles by using the MeSH vocabulary. Unlike the symptoms referred to in the CS section of OMIM (Table 1), these profiles give not only clinical, but also biological information about the disease.