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. 2009 Apr 30;37(Web Server issue):W384–W389. doi: 10.1093/nar/gkp308

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© 2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Sample functional surface page. In the example of the mitogen-activated protein kinase (PDB1ouk.A) from Homo Sapiens, SplitPocket predicts 23 pockets on the surface with customized probes. Along with the mouth (blue region), the 22th pocket (indicated with an asterisk) is the functional surface (light green) split by a ligand (084, red). Users can interact with the SplitPocket system and dynamically access the geometric and evolutionary measurements of spatial patterns on the pockets and their mouths.