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. 2009 May 14;37(Web Server issue):W222–W228. doi: 10.1093/nar/gkp379

Figure 1.

Figure 1.

A CODEHOP is a hybrid primer consisting of a 3′-degenerate ‘core’ and 5′-non-degenerate ‘clamp’ region. The DNA sequence of a CODEHOP and the amino acid multiple alignment it was derived from are shown.