Fig. 4.
The change of OSP94 in time-course after LSS. Panel A shows the change of OSP94 expression at the protein level by immunoblot analysis. In the whole cochlea, the enhancement of OSP94 protein was observed at 12h after LSS 6h (LSS 6h+12h) in comparison with the control. In contrast, there was no obvious difference in the kidney between the control and the LSS 6h+12 h. Panel B shows the time-course study of OSP94 change in the CLW after acoustic overstimulation (LSS 4h: 4hours noise-exposure at 117dB/SPL/broad band). At the transcription level, the upregulation of the OSP94 gene was until 12h after LSS 4h (p < 0.05).