Metabolism of 1,3-butadiene (10) to MHBMA (1 and 2) and DHBMA (3)
a. GSH, GSTs; b. γ-glutamyltranspeptidase; c. cysteinylglycine dipeptidase; d. cysteine S-conjugate N-acetyltransferase; EH, epoxide hydrolase; ADH, alcohol dehydrogenase; CR, carbonyl reductase