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. 2009 Jul 1;20(13):3044–3054. doi: 10.1091/mbc.E09-04-0276

Table 1.

I1-dynein components and mutants

Subunit Mol. wt. Gene/mutant Properties References
1αHC 523 ida1 (pf9, pf30) Lacks inner arm I1, slow swimming Kamiya et al. (1991)
Myster et al. (1997)
Porter et al. (1992)
1βHC 511 ida2 Lacks inner arm I1, slow swimming Kamiya et al. (1991)
Perrone et al. (2000)
IC140 140 ida7 Lacks inner arm I1, slow swimming Perrone et al. (1998)
Yang et al. (1998)
IC138 138 bop5 Partial I1 assembly, regulatory phosphoprotein part of IC138 subcomplex King et al. (1997)
Hendrickson et al. (2004)
Bower et al. (2009)
IC97 (IC110) 90 (110) Non-WD repeat protein, Porter et al. (1992)
homology to Las1/Casc1 proteins, part of IC138 subcomplex This study
Bower et al. (2009)
LC8 10 fla14 Required for flagellar assembly, part of I1 dynein, radial spokes and outer dynein arm Pazour et al. (1998)
Yang et al. (2001)
LC7a 14 oda15 Required for outer arm assembly, slow swimming, associates with I1 dynein and may interact with LC7b Pazour and Witman (2000)
DiBella et al. (2004a)
Bowman et al. (1999)
Matsuo et al. (2008)
LC7b 11 LC7/Robl family member, interacts with IC138, interacts with LC3 and DC2 of ODA Dibella et al. (2004a)
Hendrickson et al. (2004)
Tctex1 13 Dimeric protein, potential cargo binding activity, also found in cytoplasmic dynein Harrison et al. (1998)
Tctex2b 13.7 pf16-D2 Not required for I1 assembly, stabilizes I1 dynein DiBella et al. 2004a
FAP120 42 Not required for I1 dynein assembly, ankryn repeat protein, part of IC138 subcomplex Ikeda et al. (2009)