Table 1.

Effects of the Cellcultured Acanthopanax Senticosus extract on body weight gains, food intake, food efficiency ratio and blood glucose in C57BL/6J mice

	Normal		Diabetic		ANOVA1
	N-C	N-CASM	DM-C	DM-CASM	D	A	D × A
Initial body weight (g)	19.52 ± 7.13	19.08 ± 6.91	19.77 ± 9.27	20.23 ± 8.61	NS	NS	NS
Weight gain (g/12 weeks)	5.82 ± 0.78c	5.04 ± 0.36c	16.69 ± 4.27a	12.49 ± 3.45b	0.0001	0.0185	NS
Food intake (g/12 weeks)	198.24 ± 0.06	223.44 ± 0.27	199.08 ± 0.17	194.04 ± 0.07	NS	NS	NS
FER2	0.029 ± 0.007c	0.023 ± 0.0024d	0.086 ± 0.0065a	0.065 ± 0.0019b	0.0001	0.0001	0.0062
Liver weight (g)	0.85 ± 0.08b	0.88 ± 0.14b	1.54 ± 0.47 a	0.97 ± 0.11b	0.0001	0.0163	NS
Blood glucose (mg/dl)	95.98 ± 7.36c	93.49 ± 9.92c	215.56 ± 16.72a	176.92 ± 26.39b	0.0001	0.0007	1

The values represent the mean ± SD of 10 mice per group. Different superscripts in the same row indicate significant differences (p<0.05) among groups by Tukey’s test.

¹The degree of significance resulting from the two-way ANOVA is shown with effects of diet (D), administration A. senticosus (A), and the interaction of diet and administration of A. senticosus (D × A) being expressed as the numerical value or as not significant (NS) when p<0.05.

²Food efficiency ratio (FER) was calculated as weight gain weight gain (g/12 weeks)/food intake (g/12 weeks).