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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Mod Pathol. 2009 May 8;22(7):922–932. doi: 10.1038/modpathol.2009.49

Table 3.

Multivariate analysis of the relations with SIRT1 in colorectal cancer

Variable independently
associated with SIRT1		 Multivariate odds ratio
(95% confidence interval)		 P value
CIMP-high MSI-high
(vs. all other MSI CIMP subtypes)		 3.20 (1.35–7.59) 0.008
Any mucinous component (vs. 0% mucin) 1.86 (1.15–3.01) 0.01
High tumor grade (vs. low grade) 2.71 (1.19–6.15) 0.02
FASN (fatty acid synthase) 1.95 (1.03–3.69) 0.04

Multivariate logistic regression analysis assessing the relations with SIRT1 included age, sex, body mass index, tumor location, stage, grade, mucin, signet ring cells, MSI/CIMP subtype, p53, FASN, COX-2, β-catenin, LINE-1, KRAS, PIK3CA and BRAF. Only significant variables are listed.