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Blocking IL-6 bioactivity restores luminal clearing. RWPE-1/NC and rA1 cells were cultured in 3D in the presence or absence of 1 μg/ml anti-IL-6 antibody for 9 days and hollow lumen formation was quantified as before. Mean percentages ± SD of total structures counted are shown. Student's t-test, **P < 0.01.
